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DS-01® Daily Synbiotic
Benefits*
Reduces bloating and gas within 1 week†
Improves regularity and makes pooping easier within 2 weeks
Supports immune, skin, and heart health
Proven effective in 4 double-blind clinical trials
Clinical Trials
Only about 16% of supplements are clinically tested.
DS-01® has been clinically proven in 4 gold-standard, double-blind placebo controlled clinical trials.
In addition, DS-01®’s probiotic strains have been validated in 10, dose-matched gold-standard clinical trials.
The Impact of Clinical Proof
Double-blind, randomized, placebo-controlled trials (DBRCTs) are the gold standard in scientific research for various reasons, including:
Bias elimination
Control for placebo-effect
Validated efficacy
Regulatory compliance
By testing DS-01® as a full formulation, the entire product is meticulously inspected and validated for safety, tolerability, and efficacy.
Digestive Health
DS-01® is formulated to improve the frequency of your bowel movements, as well as increase stool consistency and comfort during evacuation.
Clinical Trial Results
In a 30-day study on select DS-01® strains, adults experiencing gastrointestinal troubles saw significant improvement in bowel movement frequency, consistency, and ease of defecation, compared to placebo.
DS-01®’s strains also demonstrated improvements in burning, discomfort, sense of complete emptying, and abdominal bloating.
Immune Health
DS-01® promotes a strong, resilient immune system. Dedicated strains support the gut-immune axis, which allows these systems to communicate effectively and strengthen overall immune function.
Clinical Trial Results
In a 12-week study using select DS-01® strains, participants showed a reduction in microbial translocation across the intestinal epithelial barrier and favorable circulating Th17:Treg and Th1:Th2 ratios. These findings indicate an appropriately responsive immunologic profile.
Skin Health
DS-01® is formulated with dedicated strains that support the gut-skin axis, which plays a key role in regulating inflammatory pathways between the gut and skin.
Clinical Trial Results
A 4-week study found DS-01®'s prebiotic significantly reduced wrinkle severity and demonstrated an overall shift in the skin microbiome, indicating a beneficial effect on the gut-skin axis.
A 12-week study of adults with functionally and aesthetically bothersome skin showed DS-01® strains not only improved skin appearance, but also raised quality of life scores.
Heart Health
DS-01® is formulated to help maintain healthy, in-range cholesterol and blood pressure levels. Select strains promote the production of beneficial metabolites in the gut, which supports healthy liver function and cholesterol balance.
Clinical Trial Results
In a 12-week study, DS-01® strains helped probiotic group participants maintain healthy, baseline LDL-C levels, compared to a placebo group that experienced LDL-C increases.
Additionally, the probiotic group demonstrated reinforcement of HDL-cholesterol and evidence of healthy triglyceride management within the 6-12 week timeframe.
Gut Barrier
DS-01® is formulated to strengthen and support a resilient gut barrier. Select strains replenish microflora in the gut in order to help rebuild a weakened microbiome.
Clinical Trial Results
In a 12-week study using select DS-01® strains, adults experiencing increased gut permeability showed significant reductions in circulating lipopolysaccharide (LPS), a marker of increased epithelial permeability, the cells which comprise the gut barrier.
DS-01® significantly reduced urinary lactulose excretion starting at 7 days and after 3 months of ongoing DS-01® use, compared to the placebo group— indicating both immediate and continued support for gut barrier integrity and function.
DS-01® Daily Synbiotic
Strains + Ingredients
DS-01® is formulated with 24 scientifically and clinically studied probiotic strains and a patented, non-fermenting prebiotic.
53.6 billion AFU. No refrigeration required.
Strains
Probiotic Inner Capsule
Proprietary formulation consisting of 24 probiotic strains (53.6 billion AFU) validated through strain-specific research and free of all 14 classes of allergens identified by the European Food Safety Authority (EFSA).
Digestive Health / Gastrointestinal Immunity / Gut Barrier Integrity Probiotic Blend
38.7 Billion AFU
Dermatological Health Probiotic Blend
3.34 Billion AFU
Cardiovascular Health Probiotic Blend
4.21 Billion AFU
Micronutrient Synthesis Probiotic Blend
7.32 Billion AFU
Microbiota-Accessible Polyphenolic Precursors™️ [MAPP]
400MG
Prebiotic Outer Capsule
Our prebiotic formulation consists of punicalagins concentrated from Indian pomegranate—biotransformed by gut microbes into powerful metabolites for human health.
Other Ingredients
Safety + Testing
DS-01® is held to a superior standard of quality and safety, undergoing 50+ checkpoints throughout the production process testing for purity, potency, and contaminants.
Vegan
No Preservatives
No Binders
Dairy-Tested
Gluten-Tested
Nut-Tested
Soy-Tested
Shellfish-Tested
Sesame-Tested
Corn-Tested
Prop. 65 Compliant
Glyphosate / AMPA-Tested
Supplement Facts